研究方向：

主要研究方向为(1)生物质的催化转化制备小分子药物中间体的体系设计与机制研究;(2)可降解医用材料的制备与应用;(3)小分子药物的化学合成等。

科研成果：

1) 贵州省科技厅基础研究项目,黔科合基础-[2024]青年311,光催化生物质制备高光学纯度氨基酸研究,2024.8.1-2027.7.31,5万元，在研，主持。

2) 遵义市科技局、遵义医科大学联合基金,遵市科合HZ字（2024）309号，催化浒苔衍生糖定向制备1,2-丙二醇的研究,2024.11.1-2026.10.31,5万元，在研，主持。

16. Xiao, Yuan; Xu, Shuguang; Wang, Xiaoyan; Lu, Zhiyun; Li, Jianmei*; Hu, Changwei, Enteromorpha prolifera valorization to acetol over supported Pd catalysts: Role of the support. Chemical Engineering Journal, 2023, 475, 146295 (第一作者, IF=15.1, 中科院1区)

15. Xiao, Yuan; Chen, Shiyao; Li, Jianmei*; Lu, Zhiyun; Hu, Changwei, Cooperative roles of Sn(IV) and Cu(II) for efficient transformation of biomass-derived acetol towards lactic acid production. Science of the Total Environment, 2022, 833, 155044. (第一作者, IF=9.8, 中科院1区).

14. Xiao, Yuan; Liao, Shengqi; Xu, Shuguang; Li, Jianmei*; Lu, Zhiyun*; Hu, Changwei, Selective transformation of typical sugars to lactic acid catalyzed by dealuminated ZSM-5 supported erbium. Renewable Energy, 2022, 187, 551-560. (第一作者, IF=8.7,中科院1区).

13. Xiao, Yuan; Xu, Shuguang; Zhang, Wenyu; Li, Jianmei*; Hu, Changwei*, One-pot chemo-catalytic conversion of glucose to methyl lactate over In/γ-Al₂O₃ catalyst. Catalysis Today, 2021, 365, 249-256. (第一作者, IF=5.3, 中科院2区，ESI高被引).

12. Xiao, Yuan; Xu, Shuguang; Wang, Xiaoyan; Lu, Zhiyun; Li, Jianmei*; Hu, Changwei*, Enantioselective synthesis of L-lactic acid from Enteromorpha prolifera. Energy Environment Science. (第一作者, Submitted, IF=32.5, 中科院1区)

11. Yang, Ruofeng; Xu, Shuguang; Wang, Xiaoyan; Xiao, Yuan; Li, Jianmei*; Hu, Changwei*, Sellective stereoretention of carbohydrates upon C-C cleavage enabling D-glyceric acid production with high optical purity over a Ag/γ-Al₂O₃ catalyst. Angew. Chem. Int. Ed., 2024, 63, e202403547.(第四作者,  IF=16.1, 中科院1区)

10. Xu, Shuguang; Xiao, Yuan; Zhang, Wenyu; Liao, Shengqi; Yang, Ruofeng; Li, Jianmei*; Hu Changwei*, Relay catalysis of copper-magnesium catalyst on efficient valorization of glycerol to glycolic acid, Chemical Engineering Journal, 2022, 421, 130014. (第二作者, IF=15.1, 中科院1区).

9. Xu, Shuguang; Xiao, Yuan; Li, Jianmei*; Zhang, Wenyu; Hu Changwei*, Oligomer-first mechanism in the transformation of biomass derivatives selectively to produce D-lactic acid, Chemical Engineering Journal, 2022, 432, 134359. (第二作者, IF=15.1, 中科院1区).

8. Zhou, Cuiqing; Xiao, Yuan; Xu, Shuguang; Li, Jianmei^*; Hu, Changwei^*, γ‑Valerolactone Production from Furfural Residue with Formic Acid as the Sole Hydrogen Resource via an Integrated Strategy on Au-Ni/ZrO₂, Industrial Engineering Chemistry Research, 2020, 59, 17228-17238. (第二作者, IF=4.2, 中科院2区, 化工顶刊)

7. Zhang, Wenyu; Xu, Shuguang; Xiao, Yuan; Qin, Diyan; Li, Jianmei^*; Hu, Changwei^*, The insights into the catalytic performance of rare earth metal ions on lactic acid formation from biomass via microwave heating. Chemical Engineering Journal, 2021, 421, 130014. (第三作者, IF=15.1, 中科院1区)

6. Xu, Shuguang; Tian, Qing; Xiao, Yuan; Zhang, Wenyu; Liao, Shengqi; Li, Jianmei^*; Hu, Changwei^*, Regulating the competitive reaction pathway in glycerol conversion to lactic acid/glycolic acid selectively, Journal of Catalysis, 2022, 413, 407-416. (第三作者, IF=7.3, 中科院1区)

5. Liao; Shengqi; Tian, Qing; Xiao, Yuan; Qin, Diyan; Li, Jianmei^*; Hu, Changwei^*, Glycerol valorization towards glycolic acid production over Cu based biochar catalyst. Chemsuschem, 2022, 15, e202201537. (第三作者, IF=8.4, 中科院2区 top)

4. Xu, Shuguang; Wu, Yi; Li, Jianmei^*; He, Ting; Xiao, Yuan; Zhou, Cuiqing; Hu, Changwei^*, Directing the Simultaneous Conversion of Hemicellulose and Cellulose in Raw Biomass to Lactic Acid. ACS Sustainable Chemistry Engineering, 2020, 8, 4244-4255. (第五作者, IF=8.4, 中科院1区)

3. Xu, Shuguang; Li, Jing; Li, Jianmei^*; Wu, Yi; Xiao, Yuan; Hu, Changwei^*, D-Excess-LaA Production Directly from Biomass by Trivalent Yttrium Species. iScience, 2019, 12, 132-140. (第五作者, IF=5.8, 中科院2区)

2. 李建梅，肖园，许曙光，胡常伟。一种由浒苔及其衍生物-鼠李糖、葡萄糖、木糖催化转化制备羟基丙酮的方法。中国发明专利，（已受理）

1. 胡常伟，许曙光，李建梅，吴益，肖园。一种由木糖、葡萄糖、木聚糖、微晶纤维素及玉米秸秆催化转化制备D-构型过量的乳酸的方法。中国发明专利，授权号ZL201810868191.1

核药研发团队